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Contact anaphylaxis after application of an herbal ointment containing phenonip
Contact urticaria und contact urticaria syndrome are characterized by the immediate development of itchy ares and wheals [1]. Contact urticaria may turn into contact anaphylaxis and may occur aer topical application of cosmetics, medical ointments, hair dyes, fresh food, metals, and occupational sub-stances such as cow dander, natural rubber latex, or our, grains, and feed [1, 2]. Contact anaphylaxis as a form of hypersensitivity reaction is rare but may
represent a medical emergency. Epidemiological data for contact anaphylaxis are limited and based on single case reports or small case series. Possibly,
these reactions occur more oen than estimated. e pathomechanism underlying contact urticaria syndrome and contact anaphylaxis can be IgE-me-diated, but most forms seem to results from non- immunological reactions due to the release of vaso-genic mediators [1]. Atopy seems to be a relevant risk factor for the development of contact urticaria, contact urticarial syndrome, and contact anaphy-laxis [1]
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