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Cockroach, tick, storage mite and other arthropod allergies: Where do we stand with molecular allergy diagnostics?

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Abstract Arthropods form a broad phylum within the animal
kingdom, comprising widely varying members such as insects, arachnids, crabs and centipedes. In addi-tion to common allergies to house dust mites or hy-menoptera venom, there are also rarer allergies that can be attributed to three major sources of allergens: cockroaches, ticks and storage mites. Other less known allergen sources include spiders, mosquitos, horse ies, red chironomid larvae, silver sh and lady-bugs, as well as a variety of storage pests. At present, only extract-based test systems are available for the majority of allergens in IgE-based diagnostics. Mole-cular characterisation of numerous individual aller-gens has already been carried out. However, these in-dividual allergens are only available for a small num-ber of allergen sources (e. g. cockroaches and storage mites) in routine diagnostics. Particularly in the case of allergen sources with known high cross-reactivity, the use of marker allergens is believed to improve dia-gnostics.  e currently known individual allergens of the above-mentioned allergy triggers from the ar-thropod realm are summarized and their potential use in allergy diagnostics discussed

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Informasi Detail

Judul Seri

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No. Panggil

Artikel

Penerbit

German : Springer., 2014

Deskripsi Fisik

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Bahasa

English

ISBN/ISSN

DOI: 10.1007/s40629-

Klasifikasi

NONE

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

Allergo J Int 2014; 23: 172–8

Subjek

Medicine
Allergy
cockroach
arthropod

Info Detail Spesifik

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Pernyataan Tanggungjawab

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