/var/www/fkik/app/lib/SearchEngine/DefaultEngine.php:610 "Search Engine Debug 🔎 🪲"
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SQL ⚙️: array:2 [ "count" => "select count(distinct b.biblio_id) from biblio as b left join mst_publisher as mp on b.publisher_id=mp.publisher_id left join mst_place as mpl on b.publish_place_id=mpl.place_id where b.opac_hide=0 and (b.biblio_id in(select bt.biblio_id from biblio_topic as bt left join mst_topic as mt on bt.topic_id=mt.topic_id where mt.topic like ?))" "query" => "select b.biblio_id, b.title, b.image, b.isbn_issn, b.publish_year, mp.publisher_name as `publisher`, mpl.place_name as `publish_place`, b.labels, b.input_date, b.edition, b.collation, b.series_title, b.call_number from biblio as b left join mst_publisher as mp on b.publisher_id=mp.publisher_id left join mst_place as mpl on b.publish_place_id=mpl.place_id where b.opac_hide=0 and (b.biblio_id in(select bt.biblio_id from biblio_topic as bt left join mst_topic as mt on bt.topic_id=mt.topic_id where mt.topic like ?)) order by b.last_update desc limit 10 offset 0" ]
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Abstract Allergen-specic T cells play a key role in the patho-genesis of allergic diseases through provision of help for allergen-specic B cells and control of in-ammatory responses. Allergen immunotherapy using intact allergen proteins (given either sub-cutaneously or sublingually) is clinically eective and demonstrates enduring ecacy (i. e., disease modifying). However, the requirem…
Abstract e recently published S2k-guideline on (allergen-) specic immunotherapy (AIT) provides an excel-lent overview of the evidence on allergen prepara-tions available for AIT in Germany based on the published ecacy studies. Publications based on the guideline are currently being used by the Ger-man associations of statutory health insurance physicians and German health insurance funds t…
Summary Background:e Paul-Ehrlich-Institut (PEI) pub-lished an analysis of reports of adverse drug re-actions (ADRs) in 2001 with test and therapy allergens from the period from 1991 to 2000. Pos-sible risk factors were evaluated for the ADR re-ports classied as “serious”. During the analyzed period, modied semi-depot preparations (aller-goids) induced between 0.01 % and 0.0005 % seri-…
Abstract Allergens produced by recombinant DNA technol-ogy have the ability to improve allergy diagnosis and are used as reference standards for analytical methods. In addition, the use of recombinant aller-gens in specic immunotherapy has long been con sidered potentially superior compared with the use of conventional extracts. e advantages are clear: a complex natural substance that is di…
e present guideline (S2k) on allergen-speci c im-munotherapy (AIT) was established by the German, Austrian and Swiss professional associations for all-ergy in consensus with the scienti c specialist soci-eties and professional associations in the elds of oto-laryngology, dermatology and venereology, pediatric and adolescent medicine, pneumology as well as a German patient organization (Ge…