/var/www/fkik/app/lib/SearchEngine/DefaultEngine.php:610 "Search Engine Debug 🔎 🪲"
Engine Type ⚙️: "SLiMS\SearchEngine\DefaultEngine"
SQL ⚙️: array:2 [ "count" => "select count(distinct b.biblio_id) from biblio as b left join mst_publisher as mp on b.publisher_id=mp.publisher_id left join mst_place as mpl on b.publish_place_id=mpl.place_id where b.opac_hide=0 and (b.biblio_id in(select bt.biblio_id from biblio_topic as bt left join mst_topic as mt on bt.topic_id=mt.topic_id where mt.topic like ?))" "query" => "select b.biblio_id, b.title, b.image, b.isbn_issn, b.publish_year, mp.publisher_name as `publisher`, mpl.place_name as `publish_place`, b.labels, b.input_date, b.edition, b.collation, b.series_title, b.call_number from biblio as b left join mst_publisher as mp on b.publisher_id=mp.publisher_id left join mst_place as mpl on b.publish_place_id=mpl.place_id where b.opac_hide=0 and (b.biblio_id in(select bt.biblio_id from biblio_topic as bt left join mst_topic as mt on bt.topic_id=mt.topic_id where mt.topic like ?)) order by b.last_update desc limit 10 offset 0" ]
Bind Value ⚒️: array:1 [ 0 => "%Allergy%" ]
AbstractIn recent years, the impact of environmental expo-sure to chemicals and their immunological effects, including the development of allergy, has been a topic of great interest. Epidemiologic studies indicate that exposure to endocrine-disrupting chemicals produced in high volumes, including bisphenol A (BPA) and phthalates, is ubiquitous. The links between their exposure and the developme…
Not only genetics and environmental factors are re-sponsible for the development of allergies. Epigenetic mechanisms – that are master regulators of gene transcription and thus of the accessibility and use of genome information – have been identied as a third power that is key in determining many features of allergy. So far, three epigenetic mechanisms have been identied in humans: hist…
Abstract Allergen-specic T cells play a key role in the patho-genesis of allergic diseases through provision of help for allergen-specic B cells and control of in-ammatory responses. Allergen immunotherapy using intact allergen proteins (given either sub-cutaneously or sublingually) is clinically eective and demonstrates enduring ecacy (i. e., disease modifying). However, the requirem…
Sensitivity to disinfectants plays a major role in the everyday lives of many people. Allergies, however, are far less common. Taking a detailed medical history and appropriate diagnostic allergy testing in-cluding skin test and if available in vitro tests are crucial in the professional workup of allergic re-sponses to disinfectants. Here we present a case of a classic type-I reaction to chlor…
Summary Background:Alongside hazel, alder and birch pollen allergies, ash pollen allergy is a relevant cause of hay fever during spring in the European region. For some considerable time, ash pollen allergy was not routine-ly investigated and its clinical relevance may well have been underestimated, particularly since ash and birch tree pollination times are largely the same. Ash pol-len extrac…
Abstract A relevant proportion of allergy diagnosis is accom-plished by in vitro determination of specic im-munglobulin E (sIgE) to extracts from suspected allergens. Such extracts inevitably contain glycopro-teins, which may react with patients’IgE. In the case of plant and insect allergens, the relevant epitope structure is an α-1,3-fucose on the Asn-linked sugar residue of so-called N-…
Abstract e pork-cat syndrome is an IgE-mediated allergy to pork triggered by a primary sensitization to cat dander. IgE-antibodies are directed to cat serum albumin, Fel d 2, and cross-react with porcine se-rum albumin. In contrast to meat anaphylaxis caused by IgE to α-Gal, in patients with pork-cat syndrome, symptoms occur in less than two hours aer consumption. As albumin is a thermola…
Allergy to poultry meat is rare and aects both chil-dren and adults. e prevalence of poultry meat allergy is unknown, but presumably is similar to that of red meat allergy. ere is no close relation-ship between allergy to poultry meat and allergy to red meat. Poultry meat allergy may present as pri-mary (genuine) food allergy or as secondary food allergy resulting from cross-reactivity.…
Summary In the last decade, a novel type of food allergy pre-senting with severe allergic reactions several hours aer consumption of red meat has been recognized. e allergic responses are due to IgE antibodies directed against the carbohydrate epitope galactose-α-1,3- galactose (α-Gal) found in mammalian meat. is review presents the red meat allergy syndrome in Sweden, discusses the feat…
Abstract e lifetime prevalence of allergic diseases in adults in Germany [self-reported doctor diagnosed aller-gic diseases, Study on Adult Health in Germany (Studie zur Gesundheit Erwachsener in Deutsch-land, DEGS1, 2008–2011) of the Robert Koch Insti-tute] is 8.6 % for asthma, 14.8 % for hay fever, 3.5 % for atopic dermatitis, 8.1% for contact dermatitis, 4.7 % for food allergies, and 2…