/var/www/fkik/app/lib/SearchEngine/DefaultEngine.php:610 "Search Engine Debug 🔎 🪲"
Engine Type ⚙️: "SLiMS\SearchEngine\DefaultEngine"
SQL ⚙️: array:2 [ "count" => "select count(distinct b.biblio_id) from biblio as b left join mst_publisher as mp on b.publisher_id=mp.publisher_id left join mst_place as mpl on b.publish_place_id=mpl.place_id where b.opac_hide=0 and (b.biblio_id in(select bt.biblio_id from biblio_topic as bt left join mst_topic as mt on bt.topic_id=mt.topic_id where mt.topic like ?))" "query" => "select b.biblio_id, b.title, b.image, b.isbn_issn, b.publish_year, mp.publisher_name as `publisher`, mpl.place_name as `publish_place`, b.labels, b.input_date, b.edition, b.collation, b.series_title, b.call_number from biblio as b left join mst_publisher as mp on b.publisher_id=mp.publisher_id left join mst_place as mpl on b.publish_place_id=mpl.place_id where b.opac_hide=0 and (b.biblio_id in(select bt.biblio_id from biblio_topic as bt left join mst_topic as mt on bt.topic_id=mt.topic_id where mt.topic like ?)) order by b.last_update desc limit 10 offset 0" ]
Bind Value ⚒️: array:1 [ 0 => "%Allergen%" ]
A large proportion of immunoglobulin E (IgE)-medi-ated food allergies in older children, adolescents and adults are caused by cross-reactive allergenic struc-tures. Primary sensitization is most commonly to in-halant allergens (e.g. Bet v 1, the major birch pollen al-lergen). IgE can be activated by various cross-reactive allergens and lead to a variety of clinical manifestations. In general, l…
Summary Background:e Paul-Ehrlich-Institut (PEI) pub-lished an analysis of reports of adverse drug re-actions (ADRs) in 2001 with test and therapy allergens from the period from 1991 to 2000. Pos-sible risk factors were evaluated for the ADR re-ports classied as “serious”. During the analyzed period, modied semi-depot preparations (aller-goids) induced between 0.01 % and 0.0005 % seri-…
Abstract e most common food allergies in adulthood are to plant foods (nuts, legumes, fruits, and vegeta-bles). Eliminating relevant allergens in the plant itself re presents a new approach to allergen avoid-ance for the primary, secondary, and tertiary pre-vention of food allergies. A variety of methods have been used to date with varying success in proof-of-concept investigations into t…
Abstract Essentially, allergen components oer three possi-bilities to improve in vitro IgE diagnostics: a) Allergen components can be used individually for IgE determination. b) Allergen components can be combined as a mix in one test. c) Individual allergen components can be specically added to the extract. Option (a) is currently being used most extensively in practice, while (b) represen…
Abstract Individuals suering from IgE-mediated food aller-gies are obliged to systematically eliminate the cul-prit allergen from their diet. To support allergic consumers in avoiding food allergens to make in-formed and safe purchasing choices, the European Union (EU) Food Information Regulation (FIR) im-poses a requirement to label the 13 most common allergenic foods (food groups) as ing…
Abstract Detection of specic IgE using component resolved diagnostics (CRD) identies the underlying allergen source in suspected cases of tree and grass pollen allergy. Suitable marker allergens can be used to dis-tinguish genuine sensitization to tree or grass pollen from cross-reactivity to pollen panallergens (e. g. pro-lin and polcalcins) and to overcome the lack of an-alytical specici…
Abstract Allergens produced by recombinant DNA technol-ogy have the ability to improve allergy diagnosis and are used as reference standards for analytical methods. In addition, the use of recombinant aller-gens in specic immunotherapy has long been con sidered potentially superior compared with the use of conventional extracts. e advantages are clear: a complex natural substance that is di…
Abstract Background:Beside the skin prick test, the intracu-taneous test represents the most important skin test method for detecting type-1 allergies. With the in-corporation of European directives into national law, test allergens used for allergy diagnosis are deemed medicinal products within the meaning of the German Medicinal Products Act (Arzneimittel-gesetz) and therefore require mark…
Abstract House dust mites, cats and dogs are amongst the most frequent sources of indoor allergens in Eu-rope. The fact that the allergens of house dust mites cause allergic disease through inhalation of house dust was discovered in 1964. The diagno-sis of mite allergy is regularly complicated by its often nonspecific symptoms, which frequently develop insidiously and by no means always in-clu…
Abstract Background:Over a 10 year period a decline in the rate of sensitizations to α-amylase (Aspergillus ory-zae) was observed in bakers investigated for allergic obstructive airway disease. At the same time, gluco-amylase (Aspergillus niger) was identi ed as the cur- Aspergillus niger) was identi ed as the cur- Aspergillus niger rently the most relevant allergen in sensitizations to e…