The Role of the Epigenome in Translating Neighborhoodn Disadvantage Into Health Disparities | Perpustakaan Fakultas Kedokteran dan Ilmu Kesehatan

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The Role of the Epigenome in Translating Neighborhoodn Disadvantage Into Health Disparities

Olden, Kenneth - Nama Orang; Heather A. Olden - Nama Orang; Yu-Sheng Lin - Nama Orang;

AbstractThe possible causal role of the environment in health disparities is not well understood, even though it has been a national priority for many years. Progress to investigate the relationship between genetics, environmental exposures, and health outcomes has been hampered by the lack of ana-lytical tools to quantify the combined or cumulative effect of multiple chemical and non-chemical stressors on gene expres-sion. The studies cited here provide a strong rationale for using epigenomic analysis to assess cumulative risk frommul-tiple environmental exposures over the life course. The environment-specific Bimprints^on the genome, coupledwith transcriptomics andmetabolomics, can be used to advance our understanding of the relationship between neighborhood dis-advantage and health disparities. Keywords Epigenetics.Epigenome.Genetic.DNA
methylation.Environmental health. Health disparities

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Judul Seri: -
No. Panggil: Artikel
Penerbit: USA : Springer., 2015
Deskripsi Fisik: -
Bahasa: English
ISBN/ISSN: DOI 10.1007/s40572-0
Klasifikasi: NONE
Tipe Isi: -
Tipe Media: -
Tipe Pembawa: -
Edisi: Curr Envir Health Rpt (2015) 2:163–170
Subjek: Medicine
Epigenome
Info Detail Spesifik: -
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