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Does occupational exposure to low-dose ionizing radiation affect bone marrow thrombopoiesis?

Sayed, Douaa - Nama Orang; Mostafa E Abd Elwanis - Nama Orang; Saly Y Abd Elhameed - Nama Orang; Hanan Galal - Nama Orang;

Abstract
Background: The biological effects of high levels of radiation exposure are fairly well known, but the effects of low levels of radiation are more difficult to determine because the deterministic effects do not occur at these levels.
Methods: In order to assess the risk of this exposure on BM thrombopoiesis, we measured reticulated platelets (RP) by flow cytometry in 14 hospital workers (12 technicians and 2 nurses) exposed to low level ionizing radiation in Radiotherapy Department in South Egypt Cancer Institute.
Results: There are significant difference in the percentage of RP in the peripheral circulation of the workers (p = .008) and no significant difference in the proportion of other blood elements in the peripheral circulation.
Conclusions: We think that measuring RP by flow cytometry is a rapid, non-invasive method to asses an early
affection of thrombopoiesis. This type of monitoring may be used as an indicator to detect early BM affection and to demand more controls in radiation protection.


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Informasi Detail
Judul Seri
-
No. Panggil
Artikel
Penerbit
Egypt : Springer., 2011
Deskripsi Fisik
-
Bahasa
English
ISBN/ISSN
doi:10.1186/1755-768
Klasifikasi
NONE
Tipe Isi
-
Tipe Media
-
Tipe Pembawa
-
Edisi
International Archives of Medicine 2011, 4:8
Subjek
Medicine
occupational exposure
low-dose ionizing
bone marrow
thrombopoiesis
Info Detail Spesifik
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Pernyataan Tanggungjawab
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  • Does occupational exposure to low-dose ionizing radiation affect bone marrow thrombopoiesis?
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