Artikel

Memantine effects on liver and adrenal gland of rats exposed to cold stress

---

Abstract
Background: Memantine attenuates heart stress due cold stress, however, no study focused its effects on liver and adrenal gland. We evaluated its effects on lipid depletion in adrenal gland and glycogen depletion in liver of rats exposed to cold stress.
Methods: Male rats divided into 4 groups: 1)Control (CON); 2)Memantine (MEM); 3)Induced cold stress (IH) and;
4)Induced cold stress memantine (IHF). Memantine were administrated by gavage (20 mg/kg/day) during eight
days. Cold stress were performed during 4 hours once at - 8°C. Lipid and glycogen depletion were presented as its intensity levels.
Results: Rats exposed to cold stress presented the highest glycogen (p < 0.001) and lipid depletion (p < 0.001) in liver and adrenal gland, respectively. We noted that memantine significantly reduced lipid depletion in adrenal gland and glycogen depletion in liver.
Conclusion: Memantine prevented glycogen depletion in liver and lipid depletion in adrenal gland of rats under a cold stress condition.

---

Ketersediaan

Tidak ada salinan data

Informasi Detail

Judul Seri

-

No. Panggil

Artikel

Penerbit

Brazil : Springer., 2011

Deskripsi Fisik

-

Bahasa

English

ISBN/ISSN

doi:10.1186/1755-768

Klasifikasi

NONE

Tipe Isi

-

Tipe Media

-

Tipe Pembawa

-

Edisi

International Archives of Medicine 2011, 4:5

Subjek

Medicine
Stress
liver
adrenal gland

Info Detail Spesifik

-

Pernyataan Tanggungjawab

-

Versi lain/terkait

Lampiran Berkas

Komentar

---

Anda harus masuk sebelum memberikan komentar