Artikel

Fatal cardiac arrest in an adult patient with euthyroid aanti-SSA/Ro-positive connective tissue disease: a case report

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Abstract
Background: Until recently, anti-SSA/Ro antibodies were not considered pathogenic for severe heart disease in adults. Prolongation of the mean QTc interval in electrocardiograms of adult patients with anti-SSA/Ro-positive connective tissue disease has been reported and could contribute to complex arrhythmias in such patients. Furthermore, complete heart block may also be related to these autoantibodies.
Case presentation: We describe the occurrence of fatal complete heart block in a euthyroid adult patient with undifferentiated connective tissue disease and polyglandular autoimmune syndrome type 2 associated with cardiovascular autonomic dysfunction who had normal QTc interval. The patient's serum contained anti-SSA/Ro.
Conclusion: This case might indicate that, although the adult heart conduction system may be relatively resistant to the development of anti-Ro-associated complete heart block, cardiac arrest may develop and even be fatal.

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Informasi Detail

Judul Seri

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No. Panggil

Artikel

Penerbit

Italy : Springer., 2009

Deskripsi Fisik

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Bahasa

English

ISBN/ISSN

doi:10.1186/1755-768

Klasifikasi

NONE

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

International Archives of Medicine 2009, 2:15

Subjek

Medicine
cardiac
anti-SSA/Ro-positive

Info Detail Spesifik

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Pernyataan Tanggungjawab

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