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Neural Correlates of Developmental Speech and Language Disorders: Evidence from Neuroimaging

Liégeois, Frédérique - Nama Orang; Angela Mayes - Nama Orang; Angela Morgan - Nama Orang;

AbstractDisorders of speech and language arise out of a complex interaction of genetic, environmental, and neural factors. Little is understood about the neural bases of these disorders. Here we systematically reviewed neuroimaging findings in Speech disorders (SD) and Language disorders (LD) over the last five years (2008–2013; 10 articles). In participants with SD, structural and functional anomalies in the left supramarginal gyrus suggest a possible deficit in
sensory feedback or integration. In LD, cortical and subcorti-cal anomalies were reported in a widespread language net-work, with little consistency across studies except in the superior temporal gyri. In summary, both functional and structural anomalies are associatedwithLDand SD, including greater activity and volumes relative to controls. The variabil-ity in neuroimaging approach and heterogeneity within and across participant samples restricts our full understanding of the neurobiology of these conditions—reducing the potential for devising novel interventions targeted at the underlying pathology. KeywordsSpeech disorder. Language disorder.Specific language impairment.Speech delay. Speech sound errors. Childhood apraxia of speech. Motor speech disorder. MRI. FunctionalMRI. Diffusion-weightedMRI. Communications disorders.Childhood


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Informasi Detail
Judul Seri
-
No. Panggil
Artikel
Penerbit
: Springer., 2014
Deskripsi Fisik
-
Bahasa
English
ISBN/ISSN
DOI 10.1007/s40474-0
Klasifikasi
NONE
Tipe Isi
-
Tipe Media
-
Tipe Pembawa
-
Edisi
Curr Dev Disord Rep (2014) 1:215–227
Subjek
Medicine
Language Disorders
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  • Neural Correlates of Developmental Speech and Language Disorders: Evidence from Neuroimaging
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