The glycan did it: how the α-gal story rescued carbohydrates for allergists – a US perspective | Perpustakaan Fakultas Kedokteran dan Ilmu Kesehatan

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The glycan did it: how the α-gal story rescued carbohydrates for allergists – a US perspective

COMMINS, SCOTT P - Nama Orang; MAYA R JERATH - Nama Orang; THOMAS PLATTS-MILLS - Nama Orang;

Abstract IgE antibodies to carbohydrate epitopes on aller-gens are thought to be less common than IgE anti-bodies to protein epitopes and also of much less clinical signicance. Our recent work, however, has identied a novel IgE antibody response to a mammalian oligosaccharide epitope, galactose- alpha-1,3-galactose (alpha-gal). IgE to alpha-gal has been associated with two distinct forms of anaphy-laxis including delayed allergic reactions aer eat-ing beef, pork or lamb. IgE antibody responses to alpha-gal have now been found globally. erefore, establishing the mechanism of the specic IgE antibody response to alpha-gal will be an important aspect to address as this area of research continues.

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Judul Seri: -
No. Panggil: Artikel
Penerbit: USA : Springer., 2016
Deskripsi Fisik: -
Bahasa: English
ISBN/ISSN: DOI: 10.1007/s40629-
Klasifikasi: NONE
Tipe Isi: -
Tipe Media: -
Tipe Pembawa: -
Edisi: Allergo J Int 2016; 25: 44–8
Subjek: Medicine
Glycan
Carbohydrates
Info Detail Spesifik: -
Pernyataan Tanggungjawab: -

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The glycan did it: how the α-gal story rescued carbohydrates for allergists – a US perspective

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