Artikel

Monopolar versus bipolar laparoscopic ovarian drilling in clomiphene-resistant polycystic ovaries (PCO): a preliminary study

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Abstract The objective of this study is to compare the safety and efficacy of laparoscopic ovarian drilling (LOD) utilizing monopolar versus bipolar needle in clomiphene-resistant polycystic ovaries (PCO) in infertile women. This study is a
prospective randomized comparative diagnostic trial. The pro-cedures were performed in an endoscopic unit of a tertiary care referral facility and university hospital. Eighty
clomiphene-resistant PCO patients were randomly assigned by using a computerized random table into groupA and group B for monopolar and bipolar LOD of 40 patients in each
group, respectively. The intervention was LOD using monopolar or bipolar needle in groups A and B, respectively. The main outcome measures are resumption of regular men-struation, spontaneous ovulation, and pregnancy. Both groups showed a significant postoperative improvement of menstrual patterns and hormonal profiles if compared to preoperative levels without significant difference between both groups. Spontaneous ovulation resumed in 13 (32.5 %) and 25 (62%),p= 0.007, while spontaneous pregnancywithin 1 year after LOD occurred in 9 (22.5 %) and 18 (45 %) cases
(p= 0.033) in both groups, respectively. Both monopolar and bipolar needles are effective tools for LOD in clomiphene citrate (CC)-resistant PCO infertile patients as a second-line therapy. Utilizing bipolar LOD is superior to monopolar LOD due to a significantly higher postoperative incidence of re-sumption of spontaneous ovulation and spontaneous pregnancy. Theoretical less adhesion formation following bi-polar LOD requires a second-look laparoscopy study. In the meantime, spread of bipolar LOD should be encouraged.

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Judul Seri

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No. Panggil

Artikel

Penerbit

USA : Springer., 2016

Deskripsi Fisik

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Bahasa

English

ISBN/ISSN

DOI 10.1007/s10397-0

Klasifikasi

NONE

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

Gynecol Surg (2016) 13:179–185

Subjek

Medicine
laparoscopic ovarian drilling
polycystic ovaries

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