Molecular allergy diagnostics using multiplex assays: methodological and practical considerations for use in research and clinical routine | Perpustakaan Fakultas Kedokteran dan Ilmu Kesehatan

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Molecular allergy diagnostics using multiplex assays: methodological and practical considerations for use in research and clinical routine

JÖRG KLEINE-TEBBE - Nama Orang; TJAKOB, HILO - Nama Orang; PETER FORSTENLECHNER - Nama Orang; PAOLO MATRICARDI - Nama Orang;

Abstract e availability of single allergens and their use in microarray technology enables the simultaneous determination of speci c IgE (sIgE) to a multitude of dierent allergens (> 100) in a multiplex proce-dure requiring only minute amounts of serum. is allows extensive individual sensitization pro les to be determined from a single analysis. Combined with a patient‘s medical history, these pro les sim-plify identi cation of cross-reactivity; permit a more accurate estimation of the risk of severe reac-tions; and enable the indication for spec c immu-notherapy to be more precisely established, partic-ularly in cases of polysensitization.

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Judul Seri: -
No. Panggil: Artikel
Penerbit: German : Springer., 2015
Deskripsi Fisik: -
Bahasa: English
ISBN/ISSN: DOI: 10.1007/s40629-
Klasifikasi: NONE
Tipe Isi: -
Tipe Media: -
Tipe Pembawa: -
Edisi: Allergo J Int 2015; 24: 320–32
Subjek: Medicine
Allergy
Multiplex
Info Detail Spesifik: -
Pernyataan Tanggungjawab: -

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Molecular allergy diagnostics using multiplex assays: methodological and practical considerations for use in research and clinical routine

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