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Peritoneal limited conditioning reduces postoperative pain: a randomized controlled trial in robot-assisted laparoscopic myomectomy

Storme, Nathalie - Nama Orang; Jasper Verguts - Nama Orang; Stefaan Pacquée - Nama Orang; Michèle Ampe - Nama Orang; An Creemers - Nama Orang;

Abstract Postoperative pain is related to the gas used for laparoscopy as demonstrated for 100 % nitrous oxide in 2002 by Tsereteli. In a previous trial, we demonstrated that
the use of full conditioning adding 10%nitrous oxide and 4% oxygen to the CO2pneumoperitoneum with humidification and altering the temperature of the insufflation gas, the use of Hyalobarrier gel, and the administration of 5mg dexameth-asone significantly reduced postoperative pain and decreased adhesions. As we believed that just altering the insufflation gas by adding 10 % of nitrous oxide and 4 % of oxygen
would reduce pain and adhesions by itself, we performed a randomized controlled trial on women undergoing robot-assisted laparoscopic myomectomy. Fourteen women un-dergoing robot-assisted laparoscopic myomectomy were randomized 1:1 receiving 86 % CO2+10% N2O+ 4% O2or 100 % CO2. Outcome parameters were postoperative pain (visual analog scale (VAS)) and adhesions observed at second-look laparoscopy after 14 days. Pain and painkiller intake were significantly reduced by using the altered in-sufflation gas (p< 0.05). Adhesions did not show a signif-icant difference, although the study group tended to have less adhesions (p< 0.21). Addition of 10 % N2Oand 4% O2 to the pneumoperitoneum significantly decreased postoperative pain, even in alow number of participants, which suggests a strong effect.


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Informasi Detail
Judul Seri
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No. Panggil
Artikel
Penerbit
USA : Springer., 2016
Deskripsi Fisik
-
Bahasa
English
ISBN/ISSN
DOI 10.1007/s10397-0
Klasifikasi
NONE
Tipe Isi
-
Tipe Media
-
Tipe Pembawa
-
Edisi
Gynecol Surg (2016) 13:139–146
Subjek
Medicine
myomectomy
laparoscopic
Peritoneal
laparoscopic myomectomy
Info Detail Spesifik
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Pernyataan Tanggungjawab
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  • Peritoneal limited conditioning reduces postoperative pain: a randomized controlled trial in robot-assisted laparoscopic myomectomy
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