Better compliance with hypofractionation vs. conventional fractionation in adjuvant breast cancer radiotherapy | Perpustakaan Fakultas Kedokteran dan Ilmu Kesehatan

Pencarian berdasarkan :

SEMUA Pengarang Subjek ISBN/ISSN Pencarian Spesifik

Pencarian terakhir:

$Image of Better compliance with hypofractionation vs. conventional fractionation in adjuvant breast cancer radiotherapy$

Penanda Bagikan

Text

Better compliance with hypofractionation vs. conventional fractionation in adjuvant breast cancer radiotherapy

Rudat, Volker - Nama Orang; Alaa Nour - Nama Orang; Mohamed Hammoud - Nama Orang; Salam Abou Ghaida - Nama Orang;

Abstract Background The aim of the study was to identify factors signiﬁcantly associated with the occurrence of unintended treatment interruptions in adjuvant breast cancer radiotherapy. Patients and methods Patients treated with postoperative radiotherapy of the breast or chest wall between March 2014 and August 2016 were evaluated. The radiotherapy regimens and techniques applied were either conventional fractionation (CF; 28 daily fractions of 1.8Gy or 25 fractionsof2.0Gy)orhypofractionation(HF;15dailyfractions of2.67Gy)withinverseplannedintensity-modulatedradiotherapy(IMRT)orthree-dimensionalplannedconformalradiotherapy (3DCRT). Logistic regression analysis was used to identify factors associated with noncompliance. Noncompliancewasdeﬁnedasthemissingofatleastonescheduled radiotherapy fraction. Results In all, 19 of 140 (13.6%) patients treated with HF and 39 of 146 (26.7%) treated with CF experienced treatment interruptions. Of 23 factors tested, the fractionation regimen emerged as the only independent signiﬁcant prognostic factor for noncompliance on multivariate analysis (CF; p = 0.007; odds ratio, 2.3; 95% conﬁdence interval, Prof. Dr. med. Volker Rudat vrudat@saadmedical.com, volker.rudat@gmail.com Alaa Nour ANour@saadmedical.com Mohamed Hammoud MHammoud@saadmedical.com Salam Abou Ghaida SAbouGhaida@saadmedical.com 1 Department of Radiation Oncology, Saad Specialist Hospital, 31952 Al Khobar, Saudi Arabia 1.3–4.2). No statistically signiﬁcant differences concerning the reasons for treatment interruptions could be detected between patients treated with CF or HF. Conclusion HF is signiﬁcantly associated with a better patient compliance with the prescribed radiotherapy schedule compared with CF. The data suggest that this ﬁnding is basically related to the shorter overall treatment time of HF.
Keywords Breast neoplasms · Radiotherapy · Dose hypofractionation · Radiation injuries · Risk factors

Ketersediaan

Tidak ada salinan data

Informasi Detail

Judul Seri: -
No. Panggil: artikel
Penerbit: USA : Springer., 2017
Deskripsi Fisik: -
Bahasa: English
ISBN/ISSN: DOI 10.1007/s00066-0
Klasifikasi: NONE
Tipe Isi: -
Tipe Media: -
Tipe Pembawa: -
Edisi: Strahlenther Onkol (2017) 193:375–384
Subjek: Medicine
cancer radiotherapy
Info Detail Spesifik: -
Pernyataan Tanggungjawab: -

Versi lain/terkait

Tidak tersedia versi lain

Lampiran Berkas

Quality assurance guidelines for superﬁcial hyperthermia clinical trials

Komentar

Anda harus masuk sebelum memberikan komentar