| Perpustakaan Fakultas Kedokteran dan Ilmu Kesehatan

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Epigenetic determinants of allergy and tolerance

Komentar Penanda Bagikan

KABESCH, MICHAEL

Not only genetics and environmental factors are re-sponsible for the development of allergies. Epigenetic mechanisms – that are master regulators of gene transcription and thus of the accessibility and use of genome information – have been identied as a third power that is key in determining many features of allergy. So far, three epigenetic mechanisms have been identied in humans: hist…

Edisi: Allergo J Int 2016; 25:154–9
ISBN/ISSN: DOI: 10.1007/s40629-
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Concepts and perspectives on peptide-based immunotherapy in allergy

Komentar Penanda Bagikan

TONTI, ELENA MARK LARCHÉ

Abstract Allergen-specic T cells play a key role in the patho-genesis of allergic diseases through provision of help for allergen-specic B cells and control of in-ammatory responses. Allergen immunotherapy using intact allergen proteins (given either sub-cutaneously or sublingually) is clinically eective and demonstrates enduring ecacy (i. e., disease modifying). However, the requirem…

Edisi: Allergo J Int 2016; 25:144–53
ISBN/ISSN: DOI: 10.1007/s40629-
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Climate change and air pollution

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D’AMATO, GENNARO KARL CHRISTIAN BERGMANN LORENZO CECCHI ISABELLA ANNESI-MAESANO ALESSANDRO SANDUZZI GENNARO LICCARDI CAROLINA VITALE ANNA STANZIOLA MARIA D’AMATO

e observational evidence indicates that recent re-gional changes in climate,particularly temperature increases, have already a ected a diverse setof phy-sical and biological systems in many parts of the world. Allergens patterns are also changing in res-ponse to climate change and air pollution can mo-dify the allergenic potential of pollen grains espe-cially in the presence of speci c weat…

Edisi: Allergo J Int 2014; 23: 17–23
ISBN/ISSN: DOI 10.1007/s40629-0
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