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Abstract Background: We conducted a retrospective analysis to investigate treatment results and prognostic factors of pediatric neuroblastoma patients. Methods: This retrospective study was carried out analyzing the medical records of patients with the pathological diagnosis of neuroblastoma seen at South Egypt Cancer Institute, Assiut University during the period from January 2001 and Janua…
Abstract Coronary artery diseases (CAD) inflict a heavy economical and social burden on most populations and contribute significantly to their morbidity and mortality rates. Low-density lipoprotein receptor (LDLR) associated familial hypercholesterolemia (FH) is the most frequent Mendelian disorder and is a major risk factor for the development of CAD. To date there is no cure for FH. The prim…
Abstract Chronic intestinal pseudo-obstruction (CIPO) is a syndrome characterized by recurrent clinical episodes of intestinal obstruction in the absence of any mechanical cause occluding the gut. There are multiple causes related to this rare syndrome. Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is one of the causes related to primary CIPO. MNGIE is caused by mutations in th…
Abstract Background: Global views emphasize the need for early; effective intervention against the atherogenic dyslipidemia associated with type 2 diabetes and metabolic syndrome to reduce the risk of premature cardiovascular diseases. Our aim was to determine the clinical practices and compliance among dyslipidemia with type II diabetes and hypertension in multiracial society. Method(s): S…
Abstract Strokes and TIAs, with their high cumulative mortality and morbidity rates, are occurring with increasing frequency in western population [1,4]. As such, it is vital for clinicians to provide optimal medical management in the perioperative period for those patients with this common neurological problem. This review aims to highlight the importance of the perioperative period and the s…
Abstract Since the introduction of central venous catheterization for monitoring of the venous pressure, fluid infusion and hyperalimentation, the literature has been full of serious life-threatening complications. Of these complications is the false positioning of the central venous catheter and subsequent development of pleural effusion. In this report we are describing a case of iatrogenic …
Abstract Background and Case report: Polyarteritis Nodosa (PAN) is a systemic necrotizing vasculitis that affects mediumsized and occasionally involves small arteries leading to the disruption of the internal and external elastic lamina and contribute to the development of aneurysms. Aneurysms develop at bifurcation of major blood vessels; they are prone to thrombosis, rupture and haemorrhage…
AbstractMercury (Hg) is a highly toxic, non-essential, nat-urally occurring metal with a variety of uses. Mercury is not required for any known biological process and its presence in the human bodymay be detrimental, especially to the nervous system. Both genetic and behavioral studies suggest that mer-cury levels, age (both of exposure and at testing), and genetic background determine disease…
AbstractExposure to fish intake is of particular interest for neurodevelopment. Seafood contains nutrients that are essen-tial for brain development and function. Seafood is also a potential source of well-established neurotoxic pollutants. We conducted a systematic search of the literature to review human studies on seafood intake and neurodevelopment. We identified 16 studies, most of them p…
AbstractArsenic toxicity is a worldwide health concern as several millions of people are exposed to this toxicant via drinking water, and exposure affects almost every organ sys-tem in the body including the brain. Recent studies have shown that even low concentrations of arsenic impair neurological function, particularly in children. This re-view will focus on the current epidemiological evide…