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Breast cancer is responsible for one of every three cancers diagnosed in women. In 2001, approximately 192,200 new cases of invasive breast cancer were diagnosed along with 46,600 cases of in situ breast cancer. Approximately 40,200 women and 400 men will die of breast cancer this year. Excluding skin cancer, breast cancer is the commonest cancer occurring in women and certainly the most fe…
The image on the front cover shows the crystal structure ofMexA, a periplasmic protein component of a drug efflux pump in Gram-negative bacteria. Each molecule of MexA is represented by a different color and contains a long alpha-helical coiled-coil and two beta-sheet rich domains.
Understanding about risks to people's health and their relationships with aspects of life is increasingly an essential part of daily life. New reports, new potential hazards and possibilities for revention arise all the time.
Traditional understanding of anti-tumor immunity is based on the theory of immunological surveillance and it suggests function of cytotoxic lymphocytes that can recognize tumor-specific antigens and lyse malignantly transformed cells. However tumor development is not the direct result of immune system disorders and even in case of marked immuno-deficiencies, in particular, in patients …
Apoptosis, or programmed cell death, plays an essential natural physiological role in removing cells that are superfluous, diseased, or otherwise have served their useful purpose. During apoptosis (a term derived from the Greek word for the falling of leaves from trees in autumn) living cells go through a predictable, well-choreographed series of events in which they are broken down by enz…
The aim of Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms is to present recent developments in cell survival and apoptotic pathways and their involvement in human diseases, such as cancers and neurodegenerative disorders. This requires an integration of knowledge from several fields of research, including pathology, genetics, virology, cell biology, medicine, immunology…
Emergency medical services (EMS) constitute the extension of emergency medical care into the community. Strong emergency physician leadership is essential to a safe and effective EMS system. The current EMS system in the United States started with the 1966 National Highway Safety Act, which authorized the U.S. Department of Transportation (DOT) to fund ambulances, communications, and tra…
As hospital stays shrink and community residents demand more say in their health and wellness, new models for community practice emerge. This book is the culmination of an effort to provide one of those models.
Public health nurses have been in the forefront of the public’s health since the late 1800s. Initially, public health nurses focused on prevention of diseases. Today, with the threat of new diseases, environmental disasters, and terrorism, the focus of public health nurses is on health promotion, disease prevention, public safety, and leadership in health policy. This book includes cut…