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Multiple variables influence the selection and optimization of drug therapy for each individual patient. Pharmacogenomics, the study of the influence of individual genetic variations on drug response in patients, may yield additional information to further enhance safe and effective medication use. Whereas the field originally focused on the effects of specific variants within individual genes …
Dental caries is a process which may take place on any tooth surface in the oral cavity where a microbial biofilm (dental plaque) is allowed to develop for a period of time. Although there are some 300 bacterial species in dental plaque, it is not a haphazard collection of micro-organisms. It is an ordered accumulation forming a community with a collective physiology. The bacteria in the biofil…
Clinicians can gain confidence and comfort with managing chronic pain by becoming more knowledgeable about the causes, diagnoses, and treatment options for patients with chronic pain. This can be achieved with easy-touse pain assessment strategies and tools. This book is designed to provide practical information about the pathogenesis, diagnosis, and treatment of the most common chronic pain co…
Nutrient requirements for optimum health and function of aging physiological systems often are quite distinct from those required for young ones. Recognition and understanding of the special nutrition problems of the aged are being intensively researched and tested, especially due to the increases in the elderly in the general population. In developed countries, economic restrictions and physic…
As hospital stays shrink and community residents demand more say in their health and wellness, new models for community practice emerge. This book is the culmination of an effort to provide one of those models. After working as a community health practitioner in many settings and striving to teach community health students at various levels, I have come to this book. It is a practical manual fo…
It is not difficult to understand the often held misconception that heart disease is part of ‘‘normal aging’’ and that overall cardiovascular function declines with increasing age. This rapidly growing portion of the population often does have heart disease, with hypertension, coronary artery disease, and heart failure being three conditions commonly diagnosed in many elderly patients. …
Cardiovascular diseases comprise especially the major disorders of the heart and the arterial circulation supplying the heart, brain, and peripheral tissues. Their common occurrence in most populations and the great attendant mortality, loss of independence, impaired quality of life, and social and economic costs are compelling reasons for public health concern. The epidemiology and prevention …
Bacteria are immortal in the sense that their capacity for reproduction appears limitless as long as the environment supports growth. However, this reproductive ability is gradually lost upon famine conditions. The loss of reproductive ability is one of the first signs of physiological deterioration and is followed by a collapse of the membrane integrity. The underlying molecular mechanism beh…
The experience of pain is essentially an individual, internal experience, known only to the person with the pain. We who try to help them come to it very much from the outside. What we know of it is what we can learn from that person. This knoeledge can, of course, add up to a lot of general insights into pain, but each person’s experience is defferent, and personal. The purpose of this book …
The political context has changed the face of primary health care over the last decade, hence the need for revising the content of this book, ensuring it is as up-to-date as any textbook can be. The NHS is witnessing radical reforms in an attempt to redress the balance in health across social groups in society (DoH 1999a, 1999b, 2001a). Inequalities in health influenced by structural and enviro…