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“A big book,” said Callimachus, the Alexandrian poet, “is a big evil!” Not always. There are some excellent, very big encyclopedias of cardiology, wonderful as works of reference. There are also many small books of cardiology, “handbooks” or “manuals,” which serve a different purpose, to summarize, list, or simplify. This book is designed to fill a large gap between these ext…
Esophageal cancer encompasses various types; the two predominant types are squamous cell cancer and adenocarcinoma. Their biologic and clinical features are compelling not only in the United States but worldwide as well. Other types of benign and malignant esophageal tumors, although less common, are of interest to both scientists and clinicians.
Great progress has been made in the treatment of epilepsy over the past 75 years. Although medication remains the first step when seizures begin, in some circumstances surgery is a superior remedy. For those in whom surgery is the right thing to do, all too often the person is not told about the surgical option and spends years experiencing recurrent seizures, dealing with adverse effects o…
Important Concepts in Understanding and Correctly Interpreting Biochemical Laboratory Test Result Because the practice of endocrinology is one of the most clinical laboratory dependent of medical specialties, a word of caution about overzealous reliance on biochemical testing and laboratory test results is appropriate. Because a laboratory test result by itself rarely, if ever, definitively…
chylomicron Triglyceride-rich lipoprotein made in the intestine that transports dietary lipid to various tissues throughout the body. microsomal triglyceride transfer protein (MTP) Heterodimeric lipid transfer protein found within the lumen of the endoplasmic reticulum of enterocytes and hepatocytes that promotes the transport of triglyceride and cholesteryl ester between phospholipid me…
Abortion, the medical or surgical termination of a pregnancy, is one of the oldest, most commonly practiced, and most controversial medical procedures performed in the United States. Pregnancy and abortion are intertwined with close relationships; pregnancy is of course the natural result of a sexual relationship (brief or long lasting) between a female and a male partner. The decision …
Aging is a complex developmental process that is, as yet, poorly understood. From a physical perspective, aging involves a loss of resilience or reserve capacity to respond to stressors, and this acquired vulnerability usually means that aging is associated with some greater susceptibility to illness as well as some decline in function over time. Nevertheless, the effects of aging are highly…