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INTRODUCTION Blood constitutes 6 to 8 percent of total body weight. In terms of volume, women have 4.5 to 5.5 L of blood and men 5 to 6 L. In infants and children, blood volume is 50 to 75 mL/kg in girls and 52 to 83 mL/kg in boys. The principal functions of blood are the transport of oxygen, nutrients, and hormones to all tissues and the removal of metabolic wastes to the organs of excreti…
Pyruvate kinase (PK) functions in the formation of pyruvate and adenosine diphosphate (ADP) in glycolysis. The pyruvate thus formed is subsequently converted to lactate. RBCs that lack PK have a low affinity for oxygen. Episodes of hemolysis in individuals lacking this enzyme are severe and chronic and are exacerbated by stressors such as infection.
Hematopoiesis is the process of blood cell formation. In normal, healthy adults, blood cells are manufactured in the red marrow of relatively few bones, notably the sternum, ribs, vertebral bodies, pelvic bones, and proximal portions of the humerus and the femur. This production is in contrast to that taking place in the embryo, in which blood cells are derived from the yolk sac mesenchyme. As …
Hematopoiesis is the process of blood cell formation. In normal, healthy adults, blood cells are manufactured in the red marrow of relatively few bones, notably the sternum, ribs, vertebral bodies, pelvic bones, and proximal portions of the humerus and the femur. This production is in contrast to that taking place in the embryo, in which blood cells are derived from the yolk sac mesenchyme. As …
This book is designed to provide both students and practitioners of nursing with the information they need to care for individuals undergoing laboratory and diagnostic tests and procedures. The content is presented as a guiding reference for planning care, providing specific interventions, and evaluating outcomes of nursing care. In this edition, the background information and description o…