Habibi. The Influence of Diplazium Esculentum on Cholinesterase,
Paraoxonase1, and Malondialdehid level on Vegetable Farmers Using
Pesticides in Kanreapia Village, Tombolopao District, Gowa . Regency.
(Supervised by Suryani As’ad, Agussalim Bukhari, A. Armyn Nurdin)
This study aims to determine the effect of Diplazium esculentum enzyme
cholinesterase, paraoxonase-1 (PON1) and malondialdehyde (MDA)
levels in farmers exposed to pesticides. This study uses a Randomized
Controlled Trial (RCT) experimental design, in which the researcher
allocates research samples to the experimental group and the control
group randomly based on the criteria determined by the researcher,
double-blind. The population in this study were all pesticide-using
vegetable farmers in Kanreapia Village, Tombolopao District, Gowa
Regency, which consisted of 375 people. While the number of samples
was 42 people (21 people in the intervention group and 21 people in the
control group). Based on the paired t test, the value in the intervention
group was p = 0.004 and the control p = 0.032 and the results of the
unpaired t test obtained a significance value of p = 0.047 which means
there is an effect of giving Diplazium esculentum on cholinesterase levels.
The results of the Wilcoxon paraoxonase-1 showed that the value in the
intervention group was p=0.005 and the control group p=0.520.test Mann
Whitney U obtained a significance value of p = 0.043 which means that
there is an effect of giving Diplazium esculentum levels paraoxonase-1
Whereas Wilcoxon malondialdehyde (MDA) The value in the intervention
group was p=0.424 and the control p=0.375.test Mann Whitney U showed
a significance value of p=0.242 , which means that there was no
significant effect of giving Diplazium esculentum on malondialdehyde
levels in pesticide-using vegetable farmers. There is an effect of Diplazium
esculentum on enzyme cholinesterase, and paraoxonase-1 (PON1) levels,
and there is no effect of Diplazium esculentum on malondialdehyde (MDA) in farmers exposed to pesticides
Keywords : Diplazium esculentum; enzyme cholinesterase, paraox