Abstract
Background:We evaluated the presence of ductal carcinoma in situ (DCIS) in core needle biopsies (CNB) from invasive ductal lesions.
Methods:Retrospective study, which analyzed 90 cases of invasive ductal carcinoma lesions. The percentage of DCIS was quantified in each specimens obtained from CNB, which were compared to the surgical specimens. CNB and surgical specimens were evaluated by the same pathologist, and the percentage of DCIS in CNB was evaluated (percentage) and divided into categories. We considered the following parameters regarding the amount of DCIS: 1=0; 2=1 for 5%; 3=6 for 24%; 4=25 for 50%; 5=51 for 75% and 6=76 for 99%. The number of fragments and the histological pattern of DCIS was found.
Results:We found the following results regarding the distribution of the percentage of DCIS in the CNB: 1 = 63.3%;
2 = 12.2%; 3 = 12.2%; 4 = 5.6%; 5 = 1.1% and 6 = 5.6%. The logistic regression analysis showed that CNB percentages above 45% reflected the presence of DCIS in the surgical specimen in 100% of the cases (p