AbstractSince the identification of Fetal Alcohol Syndrome over 40 years ago, much has been learned about the detrimen-tal effects of prenatal alcohol exposure on the developing brain. This review highlights recent neuroimaging studies within the context of previous work. Structural magnetic resonance imaging has described morphological differences in the brain and their relationships to cognitive deficits and measures of facial dysmorphology. Diffusion tensor imaging has elaborated on the relationship between white matter mi-crostructure and behavior. Atypical neuromaturation across childhood and adolescence has been observed in longitudinal neuroimaging studies. Functional imaging has revealed dif-ferences in neural activation patterns underlying sensory pro-cessing, cognition, and behavioral deficits. A recent functional connectivity analysis demonstrates reductions in global net-work efficiency. Despite this progress, much remains unknown about the impact of prenatal alcohol exposure on the brain, and continued research efforts are essential. KeywordsFetal. Alcohol.Brain. Development.FASD. FAS.Neuroimaging.Imaging. Prenatal