As the title suggests, the present text is aimed at providing basic knowledge and the state of the art on the biology and mechanics of blood flows. Due to its length, this book has been divided into two parts, the criterion being the size of the biological domain used to extract input data required to model the cardiovascular system (CVS). The subtitles of each part thus reflect
this subdivision.1 The present Part II, Mechanics and Medical Aspects refers to the macroscopic scale. It contains chapters on anatomy, physiology, and continuum mechanics, as well as pathology of the vasculature walls, including the heart, and their treatment. Methods of numerical simulations are given and illustrated in particular by wall diseases. The main information about cardiovascular biology is provided in Appendix A; biology of the cardiovascu-lar system is given in Part I. Mechanical data and concepts are summarized in Appendix B, as well as major information on flows in deformable conduits. Basic information on numerical simulation methods are given in Appendix C, emphasizing the computational methods used by the author to simulate blood dynamics in large vessels.