AbstractAlthough the scientific community has recognized the effects of prenatal alcohol exposure on development for over 40 years, the empirical study of positive behavioral in-terventions and family support programs for people with fetal alcohol spectrum disorders (FASD) has only just emerged over the last 10 to 15 years. In this time, dedicated researchers have developed innovative programs that have generally pro-duced large effects and have been acceptable to children with FASD and their families. This body of work demonstrates that children with FASD can benefit from interventions that are appropriately tailored to their neurodevelopmental disabilities. Despite this progress, much work lies ahead to meet the sig-nificant needs of people with FASD. This review evaluates available sources of information, including theoretical and Lived Experiencemodels, empirical evidence on existing pro-grams, and best practice guidelines, to guide future research priorities and clinical practice. Three priorities for future inter-vention research are offered. KeywordsFetal alcohol spectrumdisorders. Intervention. Positive behavior support. Family support. Empirically-supported interventions