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The PANDAS Controversy: Why (and How) Is It Still Unsettled?



AbstractAcute-onset OCD and/or tics in children, known by the term Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus (PANDAS), has been a focus of pediatric developmental and psychiatric research for nearly three decades. Studies have suggested that this condition results from molecular mimicry, in which anti-basal ganglia antibodies target brain proteins.While the pathogenesis of this condition is still widely debated, the clinical phenotype has shown consistent features and evidence that the dramatic symptoms cause substantial impairment in the child and in family functioning. Keywords PANDAS.PANS.OCD. Tics. Streptococcal infections



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Judul Seri
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No. Panggil
Artikel
Penerbit Springer : USA.,
Deskripsi Fisik
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Bahasa
English
ISBN/ISSN
DOI 10.1007/s40474-0
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NONE
Tipe Isi
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Tipe Media
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Tipe Pembawa
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Edisi
Curr Dev Disord Rep (2014) 1:236–244
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