Abstract Uterine polyps can cause abnormal bleeding in women. Conventional practise is to remove themunder general anaesthesia but advances in technology have made it possible
to perform polypectomy in the office setting. We conducted a patient-preference study to explore women’s preferences for treatment setting and to evaluate the effectiveness and treatment experience of women undergoing uterine polypectomy. Three hundred ninety-nine women with abnormal uterine bleeding who were found to have uterine polyps at diagnostic hysteros-copy were recruited. Office polypectomies were performed in office hysteroscopy clinics, and inpatient procedures were un-dertaken in operating theatres. Three hundred twenty-four of 399 (81 %) expressed a preference for office treatment. There was no difference found between office treatment and inpatient treatment in terms of alleviating abnormal uterine bleeding as assessed by patients and in improving disease-specific quality of life. Acceptability was lower and patient pain scores were significantly higher in the office group. When offered a choice of treatment setting for uterine polypectomy, patients have a preference for office over inpatient treatment. Ambulatory gy-naecology services should be available within healthcare sys-tems to meet patient demand