AbstractBullying is a significant public health problem in the United States that affects youth functioning in multiple domains. Much of the research on bullying to date has focused on children, however, leaving gaps in the literature with respect to understanding bullying among adolescents. In particular, less is known about how adolescents con-ceptualize bullying, what predicts and is associated with bullying involvement among adolescents, and how pre-vention programs might address the unique needs of mid-dle and high school students. This special issue proposes that a multidisciplinary perspective might be particularly useful in better understanding bullying among adolescents and determining how to design more effective interven-tions and prevention programs for this age-group. The current article introduces the special issue by briefly dis-cussing what is known about bullying in adolescence and considering three disciplines (computer science, big data, and virtual communities; media studies; anthropology) that are particularly well situated to move the field forward. Next, this article reviews teen pregnancy prevention efforts, as an example of another adolescent public health concern that has been addressed successfully using a multidisciplinary approach. The article concludes with an overview of the three manuscripts that are part of the special issue. KeywordsBullying Adolescence Multidisciplinary